|
KMID : 0897520230280020071
|
|
Journal of Korean Association of Social Psychiatry
2023 Volume.28 No. 2 p.71 ~ p.79
|
|
|
Risk Factors for Delirium after Hip surgery under General Anesthesia using Remimazolam: a Retrospective study
|
|
Kangv Seung-Jae
Jun In-Jung
Kim Won
Chang Yoon-Young
Sohn Bo-Kyung
Lee Dong-Woo
|
|
|
Abstract
|
|
|
Objectives: This study aims to determine the incidence of delirium and delirium-related factors in patients undergoing hip surgery who were under remimazolam, a drug recently introduced and used in Korea.
Methods: This is a retrospective study based on clinical information of patients aged ≥60 years who underwent hip fracture surgery after anesthesia with remimazolam from March 1, 2021 to October 31, 2022. We investigated the incidence of delirium during the admission period and delirium-related factors by analyzing the current medical and social history, and pre- and postoperative blood tests results.
Results: Of the 106 patients, 46 (43.40%) developed postoperative delirium. Chi-square and t-tests showed that age (p=0.004), years of education (p=0.028), history of stroke (p=0.016), psychiatric history (p=0.015), presence of preoperative electrolyte imbalance (p=0.036), and preoperative blood glucose levels (p=0.023) were significantly different between those who developed postoperative delirium and those who did not. In logistic regression analysis, the risk of the occurrence of delirium was significantly related to increasing age (B=0.083, OR=1.086, 95% CI=1.007-1.172, p=0.032), history of stroke (B=1.312, OR=3.714, 95% CI=1.066-12.939, p=0.039), preoperative electrolyte imbalance (B=1.028, OR=2.796, 95% CI=1.021-7,659, p=0.046), and high preoperative blood sugar levels (B=0.019, OR=1.019, 95% CI=1.004-1.034, p=0.014).
Conclusion: This study found that the incidence of delirium following orthopedic hip surgery using remimazolam was not significantly different from that using conventional anesthetics if indirectly compared to previous studies in similar populations. Moreover, if we use remimazolam, we should consider the delirium-related factors and treat modifiable factors for delirium prevention.
|
|
|
KEYWORD
|
|
|
Delirium, Hip surgery, Remimazolam
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|